Doctor X Will Build A Creature.
The following story was written by journalist Allen Walker and appeared in the October 2016 issue of Catchall, an alt-weekly for which he is a feature writer. It’s reprinted here with the author’s permission. His articles have also appeared in Matrix, Road Hogs, Elsewhere, and other publications.His essay Patagonia Dreamin’ is included in the anthology The Journey Of A Thousand Miles. Other stories by Allen Walker that have appeared here are A Werewolf Problem In Central Indiana, Living Or Dead Is Purely Coincidental (Part 1, Part, 2, Part 3, Part 4), That Was The Year That Was, and Submerged.
“Isn’t he magnificent?” Dr. Xavier says as she flips the carcass over on the exam table. Magnificent is not the word that comes to my mind. In fact I feel slightly ill. The glare of burnished metal brings out details that might normally only be seen under a magnifying glass, but here there’s nothing between us. His–since we’re calling it a he–legs are folded inward toward the center of its body in the classic death position of normal-sized specimens, and he gives off a musky, slightly sweet odor reminiscent of rotting hay. Dr. Xavier is gently prying the legs apart to expose the underside.
“How can you tell he’s a he?” I ask quietly, taking a step back.
She presses gloved fingers to different parts, using technical terms and explaining that if it were a female this would be longer, that would be shorter. She points to a cluster of bulbs at its rear. “The spinnerets would be much bigger, although with the original species we bred from there’s not that much difference in size between the males and females. That’s one reason we chose from the family Sparassidae.”
That’s a relief, I think. I’d read that in some species the female is ten times bigger, or more, than the male. The specimen in front of me is big enough as it is, thank you very much.
I am, of course, at the renowned and controversial Praetorius Institute in eastern Tennessee, near where the state shares borders with North Carolina and Virginia. The Institute, or PI as everyone here likes to call it, has been praised, criticized, celebrated, demonized, and even scrutinized by government officials and watchdogs, and yet its work has gone on, thanks in part to its defenders. When scientists first cloned Dolly the sheep in the late twentieth century that was controversial too, but was a great leap forward in understanding biology. And this breakthrough has great practical potential as well.
At least that’s what the PI’s researchers and its defenders argue. There are a lot of people, including me, who still have trouble with the idea of a spider three feet long roaming around.
Since no human, alive or dead, has ever seen such a thing it’s difficult to find the right words. The joints of its cylindrical legs are machine-like, and yet they’re hairy. The upper, narrower thorax is mostly bare, a dull black, with a look of molded plastic. The round abdomen is covered with smooth gray fur with bands of dark brown.
Dr. Xavier’s straight dark hair hangs down as she turns it right side up again and deftly moves it around. I ask her how much it weighs.
“Alive he was twelve, maybe thirteen kilos. About eleven now. They dry out quickly. Would you like to touch it?” She grins. “Unless you think it’ll bite.”
That’s exactly what I’m thinking. Intellectually too I know there‘s no real danger. On my arrival I am given a press packet and taken straight to Dr. Xavier‘s corner office where pictures of her partner and two children decorated her desk along with pictures of spiders. A web knitted from yarn hangs in front of the window overlooking the valley. After offering me some tea in a Spider-Man mug Dr. Xavier starts to give me her prepared speech. Spider silk is the holy grail of engineering materials. As strong as steel but extremely light it has limitless possibilities for everything from medicine to construction to space exploration. The problem has always been getting it. The Praetorius Institute, like some other organizations, started experiments with implanting spider genes in female goats which would then produce spider silk from their milk glands. It had limited success but the silk had to be extracted from goats’ milk and required a lot of processing. “We knew we could do better,” Dr. Xavier says. “And the answer was simple. Instead of cutting out genes from spiders and sticking them somewhere else we had to go straight to the source.” She then pulls a slim book from behind her desk and hands it to me. It’s a children’s book of prehistoric creatures and she’s opened it to a picture of a primeval forest with giant insects.
“The world used to have giant dragonflies and meter-long millipedes,” she says. “There may even be mega-spider fossils we just haven’t found yet. One reason bugs don’t get so big anymore is the atmosphere used to have as much as forty percent more oxygen than it does now.”
“So,” I say, “if one of your spiders were to get loose–“
”It would suffocate before it could even leave the building.” But what if there’s some reflex that causes even the dead ones to react? I wish I’d gone with the group tour instead of the solo option when I accepted the invitation. Then when there was a call for volunteers I could hang back, let someone else put their hand in harm’s way. As I think this Dr. Xavier comes around to my side of the table and grabs my arm. She puts my hand on the abdomen.
“Just stroke it. See? It’s like petting a cat.”
I wonder if this will affect my feelings for my real cat, Emily, whose fur is also gray. In fact it’s nothing like petting a cat. The fur is soft, but the body underneath is hard. It’s like petting a mannikin wearing a mink stole.
“We thought they’d be prickly,” Dr. Xavier goes on, “but they’re surprisingly soft. That’s just one thing. Look at the feet.” She bends a hairy leg backwards. The underside is covered with deep grooves that form circles, like a fingerprint. “It’s almost like a gecko,” she says. “Fortunately they can’t climb. Then she turns the spider’s face to me. I step back, but she doesn‘t notice. “And look at how the palps and mandibles are different from what you’d find in a regular spider. Even after three decades we can’t always predict what will happen when we tinker with DNA to this degree.” Above the broad beak six greenish orbs seem to glower at me.
We go to lunch in the PI’s cafeteria. On a lower floor than Dr. Xavier’s office it overlooks a small artificial pond and the surrounding forest. It’s crowded and I’m reminded that the spiders are just one of a dozen or so projects that sound like science fiction going on at the PI, and yet no one here looks like a mad scientist. Least of all Dr. Xavier. Over our lunch of Caesar salads topped with seared steak I bring up the controversial nature of the mega-spiders. She sighs.
“I’ve had this debate with practically everyone I know, including most of my family. I don’t want to be glib about anyone’s feelings but humans have been manipulating genes for as long as we’ve had agriculture. The mega-spiders are as natural as a hybrid tomato. You want an abomination? Look at a Labradoodle.”
To try and relieve some of the tension I change the subject.
“What made you want to study genetics? Your parents weren‘t scientists.”
“No. My father wanted to be but he went into hardware instead to support my grandparents after they came over from Vietnam. He encouraged me, though, and I’ve always had an interest in bugs. I got a Barbie Dream House one Christmas and used it to raise palmetto bugs.”
“Giant palmetto bugs?”
She laughs. “As big as they get. I was more interested in their life cycle and behavior, though. It was reading about fruit flies that got me into genomics. The idea that everything we are is determined by a single long molecule just fascinated me.” She puts her hand over her mouth as she thoughtfully chews a larger piece of steak. “The problem with mega-spiders, of course, was where to start.”
“Which came first: the spider or the egg?” I start to laugh but she pounces on this.
“Exactly! We couldn’t just flip a switch and make spiders grow big. That’s why it took more than three decades of research before we could get them to this size. It took several generations and more than two dozen changes to their DNA.”
She continues as she cuts a piece of blackened steak into smaller pieces. “There were some terrible mistakes too, horrible things. You wouldn’t believe some of the challenges we faced. But we learned a lot too. Like, what do you feed a three-foot spider? Normal spiders liquefy their prey’s guts and suck it out, but they’re feeding on insects, other arachnids, things with exoskeletons. The genes we changed triggered other changes too. Like beaks. We feed the mega-spiders rats. They paralyze them and swallow them whole.” She takes another bite of steak. “A lot of fur comes out in their scat.”
I push my salad away and make a mental note to suggest that on future tours she save this information for after lunch.
She pushes her salad away too. “Come on. It’s time for you to meet the kids.”
At first “the kids” are no-shows, but their enclosures are fascinating. Through clear plastic walls I can see ferns and what look like small palm trees shrouded in mist.
“Cycads,” Dr. Xavier tells me. “Also horsetail, moss, liverworts. They’re what even some scientists call ‘primitive plants’ because they’ve been around so long. They seem to tolerate the high oxygen better than other plants, and we hope it makes the spiders more comfortable. We have to keep it humid too, for the spiders. Some of their wild cousins live in the desert, but these, well, just to maintain their body mass they need more of everything.”
The plants in the enclosures look more futuristic than prehistoric. Also surprising is the absence of any sign of webs. This is a source of frustration for Dr. Xavier and her entire team.
“Tarantulas don’t build webs but they can spin silk, and their size made them an obvious choice. We just assumed we’d be able to extract silk from them. So far that’s been harder than we thought it would be. Maybe with what we’ve learned we can try with another family, maybe Aranea or Nephila, but that would be like starting all over.”
As she speaks one of the spiders creeps out of the mist. As it moves across the mossy floor its slow plodding is fascinating to watch. I wonder if it’s stirring up genetic memories, perhaps passed down from some of my mammalian ancestors. Its movements are deliberate, reaching out gently with its forelegs.
Dr. Xavier tells me they have nine in all, kept in separate enclosures. Originally they were kept together until one of the females turned aggressive and killed her sisters.
“And when the males started hunting in packs, circling around the rats we put in there for them, we thought maybe we should keep them separate.”
This spider is brighter in color than the one we examined earlier in the lab, with coppery fur. As it turns to face me a each of its dark green eyes is bisected by a single beam of light, like a precious stone.
I hear Dr. Xavier talking to someone behind me, but I’m too entranced by the spider to pay attention. Then she steps up next to me and says , “This is Carl.”
“Hello Carl,” I say, looking down at the spider. Then I jump as a bass baritone voice says, “Hello to you too.”
I turn around. A stocky man in a dark blue coat is standing next to Dr. Xavier. He puts out his hand.
Dr. Xavier apologizes. “I’ve got to go make a call, but Carl can keep showing you around.” As she hurries away Carl and I turn back to the spider.
“Creepy, ain’t they?” says Carl. He chuckles.
“I’m not sure that’s the right word,” I say. “In fact I’m having trouble finding the right words.”
“Come with me.”
In the elevator Carl swipes his ID card and a few moments later we step out onto the roof of the Praetorius Institute.
“I like to come up here once in a while for a little fresh air and a think,” he says.
“What do you think about?”
He chuckles again. “Anything. Nothing. Just take it all in.”
I step to the edge and look out at the forest below. In the distance I can see a low cloud settled over a hill. It looks like a web.
FROM: THE GALACTIC COUNCIL, MILKY WAY
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